Most important fact about Actonel

Although our bones seem solid and stable, they actually undergo constant renewal. Specialized cells called osteoclasts draw used calcium out of the bones while other cells called osteoblasts replace it. Especially after menopause, this process can get out of balance. Calcium starts to leach out of the bones faster than it can be replaced, leading to the brittle-bone disease called osteoporosis.

Actonel combats this problem by reducing the activity of the osteoclasts and slowing the loss of calcium from the bones. It is prescribed for postmenopausal women, both to prevent osteoporosis and to strengthen the bones once the disease has begun. It is also used to prevent or treat osteoporosis resulting from therapy with steroid medications, and it is used in the treatment of Paget's disease, a condition in which patches of bone become softened and enlarged.

Both Actonel and a similar drug called Fosamax are members of the family of drugs called bisphosphonates.

Actonel not only stops the bone loss of osteoporosis, but actually reverses the disease and increases bone mineral density. As the bones grow stronger, your chances of sustaining a fracture decline.

How should you take Actonel?

Three types of Actonel are available: a 5-milligram and 30-milligram tablet that can be taken daily, and a 35-milligram tablet that's taken once a week. The tablets should be taken at least 30 minutes before the first food or drink of the day other than water. Take the pill while standing or sitting in an upright position and wash it down with a full 6 to 8 ounce glass of plain water (do not use coffee, tea, juice, milk, or other dairy products). Swallow the tablet whole, do not chew or suck on it. Do not lie down for 30 minutes after taking the medication.

Other treatment measures typically include weight-bearing exercise, reduction of excessive smoking and drinking, and supplemental calcium and vitamin D if you don't get enough in your diet. If you require calcium supplements, or use any medications containing calcium, aluminum, or magnesium, avoid taking them at the same time of day as Actonel.